The peripheral nervous system mostly develops from the neural crest cells. The neural crest cells are groups of ectodermal cells that temporarily form an intermediate zone between the neural tube and surface ectoderm. These cells migrate and differentiate into the sensory ganglia, sympathetic neuroblasts, Schwann cells, pigment cells, odontoblasts, meninges and cartilage cells of the branchial arches.
Neuroblasts of the sensory ganglia penetrate the dorsal part of the neural tube and mostly end in the dorsal horn, thus giving rise to the dorsal root neurons. The peripherally growing processes of the neuroblasts in the sensory ganglia terminate in the sensory receptor organs. |
